Mumunda weinjiniya yemakemikari, kuwana kwakanyatso uye kunoshanda kupatsanura uye kucheneswa maitiro kwakakosha zvakanyanya. Chimwe chezvishandiso zvakakosha mundima iyi ndeyekudhonza uye yekumisikidza unit. Iyi yepamusoro unit inosanganisa huwandu hwetekinoroji kubvisa, kupatsanura uye kuisa pfungwa pazvinhu zvinodiwa kubva mumisanganiswa. Chikwata ichi chinoita basa rakakosha mumaindasitiri akasiyana siyana, kubva pamishonga yemishonga kusvika pakunatsa petroleum.
Iyo huru yekushanda musimboti wekubvisa uye yekumisikidza unit ndeyekusarudza kunyungudutsa chimwe kana kupfuura chinodiwa chikamu kubva musanganiswa uchishandisa yakakodzera solvent. Iyi nzira inonyanya kukosha kana ichitsaura makomisheni ekukosha kubva mumisanganiswa yakaoma, sezvo inobvumira kutorwa kwakanangwa kwemarudzi anodiwa. Nekushandisa zvakasiyana zvinonyungudutsa, tembiricha, kumanikidza uye nzira dzekuparadzanisa, mainjiniya anogona kukwenenzvera nzira yekubvisa kuti inyatsoshanda.
Imwe yemabhenefiti makuru ekushandisa kudhirowa uye yekumisikidza unit kugona kusarudza nekusarudza zvikamu uchisiya zvisingadiwe kumashure. Kusarudzwa uku kunogonesa kuparadzaniswa kwemishonga inokosha kubva kune tsvina, zvichiita kuti zvive zvakachena zvakanyanya uye zvakagadziriswa zvigadzirwa zvekupedzisira. Semuyenzaniso, muindasitiri yemishonga, zvidimbu zvekubvisa zvinoshandiswa kupatsanura mashandiro emishonga emishonga (APIs) kubva kumiti kana zvimwe zviwanikwa. Izvi zvinogonesa kugadzirwa kwemishonga inoshanda zvikuru ine tsvina shoma.
Imwe mukana wakakosha wekubvisa uye yekumisikidza mayunitsi ndiko kuwedzera kwekuita kwemakemikari maitiro. Nekuisa pfungwa pazvinhu zvinodiwa, mainjiniya anoderedza huwandu hwemhinduro yekubvisa, iyo inoderedza zvinotevera kugadzirisa zvinodiwa. Iyi optimization inoderedza kushandiswa kwesimba, kushandiswa kwesolvent uye mutengo wese wekugadzira. Pamusoro pezvo, mhinduro dzakamisikidzwa dzinowanzo kuvandudza maitiro ekudzika senge crystallization kana distillation, zvichiwedzera kuwedzera kubereka uye kuderedza mitengo.
Kubvisa uye kusungirira mayuniti anoshandisa nzira dzakasiyana dzekubvisa senge liquid-liquid extraction (LLE), solid-phase extraction (SPE) uye supercritical fluid extraction (SFE), zvichienderana nehunhu hwezvisanganiswa uye mhedzisiro yaunoda. LLE inosanganisira kunyungudutsa zvikamu muzvikamu zviviri zvisingagoneki zvemvura, kazhinji inonyungudutsa ine aqueous solvent uye organic solvent. SPE inoshandisa matrices akasimba akadai seakabatidzwa kabhoni kana silica gel kusarudza adsorb inodiwa zvinhu. SFE inoshandisa mvura iri pamusoro penzvimbo yakakosha kuti iwedzere kudhirowa. Imwe neimwe tekinoroji ine zvayakanakira uye inosarudzwa zvinoenderana nezvinodiwa chaizvo maitiro.
Pamusoro pekubvisa, iyo yekusimbisa chikamu chemudziyo yakakosha zvakaenzana. Kuisa pfungwa kunowanikwa nekubvisa solvent kubva mumhinduro yekubvisa, ichisiya chero yakagadziriswa mhinduro kana yakasara yakasimba. Iyi nhanho inova nechokwadi chekuti zvinhu zvinodikanwa zviripo muhuwandu hwakanyanya, zvichiita kuti zvive nyore kuenderera mberi nekugadzirisa kana kuongorora. Matekinoroji anoshandiswa pakusunga anosanganisira evaporation, distillation, kuomesa-kuomesa, uye membrane kusefa, pakati pevamwe.
Evaporation inzira inoshandiswa zvakanyanya yekuisa pfungwa pamhinduro. Pakupisa, chinonyungudutsa chinobuda, chichisiya munyu wakazara. Iyi nzira inonyanya kukosha kune zvikamu zvinopisa zvinopisa. Kune rumwe rutivi, distillation inoshandiswa apo nzvimbo yekubikira yezvinonyungudutsa yakanyanya kuderera pane iyo yechikamu chinodiwa. Distillation inopatsanura zvinonyungudutsa kubva kune zvimwe zvikamu nekudziisa uye kudzoreredza mhute. Kuomesa nechando kunoshandisa kutonhora-kunyungudika kutenderera uye kuderedzwa kumanikidza kubvisa chinonyungudutsa, kuchisiya chakaoma, chakazara chigadzirwa. Chekupedzisira, membrane kusefa inoshandisa permselective membranes kuti iparadzanise solvent kubva kune yakaomeswa zvikamu.
Mukupedzisa, kudhirowa uye kusungirira zvikamu zvinotora basa rakakosha mune akasiyana makemikari maitiro mumaindasitiri akasiyana. Iyo unit inosanganisa matekiniki ekubvisa akadai seLLE, SPE uye SFE kusarudza kubvisa zvinodiwa kubva mumusanganiswa. Pamusoro pezvo, inoshandisa nzira dzakasiyana-siyana dzekugadzirisa, kusanganisira evaporation, distillation, kuomesa-kuomesa uye membrane filtration, kuwedzera huwandu hwechinhu chinodiwa. Nekudaro, iyo unit inogonesa inoshanda uye inodhura-inoshanda yekuparadzanisa uye yekucheneswa maitiro, zvichiguma nemhando yepamusoro-yakaiswa zvigadzirwa. Ingave mumishonga, kuchenesa oiri kana mamwe maindasitiri emakemikari, kudhirowa uye kumisikidza zvikamu chishandiso chakakosha mukutsvaga kugona.
Nguva yekutumira: Aug-23-2023